JUP anticorps (AA 726-730)

N° du produit ABIN5689306

L’anticorps Lapin Polyclonal anti-JUP a été validé pour WB. Il convient pour détecter JUP dans des échantillons de Humain et Rat.

Aperçu rapide pour JUP anticorps (AA 726-730) (ABIN5689306)

Antigène: JUP (Junction Plakoglobin (JUP))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JUP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-JUP anticorps

Épitope: AA 726-730

Specificité: This antibody detects endogenous levels of total gamma-Catenin protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: gamma-Catenin antibody was raised in was raised against a peptide sequence around aa.726~730 (I-D-T-Y-S) derived from Human gamma-Catenin.

Information d'application

Indications d'application: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store antibody at -20°C for up to one year.

Détails sur JUP

Antigène: JUP (Junction Plakoglobin (JUP))

Autre désignation: gamma Catenin 

Sujet: Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton

Poids moléculaire: 83 kDa

ID gène: 3728

NCBI Accession: NP_002221

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location