c-FOS anticorps (AA 28-32)
Aperçu rapide pour c-FOS anticorps (AA 28-32) (ABIN5689379)
Antigène
Voir toutes c-FOS (c-Fos) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 28-32
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Specificité
- This antibody detects endogenous level of total C-Fos protein.
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Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogène
- C-Fos antibody was raised against a peptide sequence around aa.28~32 ( S-Y-Y-H-S) derived from Human C-Fos.
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Indications d'application
- Western Blot: 1:500~1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store antibody at -20°C for up to one year.
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- c-FOS (c-Fos) (c-Fos)
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Autre désignation
- C Fos
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Sujet
- Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
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Poids moléculaire
- 62 kDa
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ID gène
- 2353
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NCBI Accession
- NP_005243
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UniProt
- P01100
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Pathways
- S100 Proteins
Antigène
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