VASP anticorps (AA 236-240)
Aperçu rapide pour VASP anticorps (AA 236-240) (ABIN5689502)
Antigène
Voir toutes VASP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 236-240
-
Specificité
- This antibody detects endogenous level of total VASP protein.
-
Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
-
Immunogène
- VASP (Ab-239) antibody was raised against a peptide sequence around aa. 236~240 (K-V-S-K-Q) derived from Human VASP.
-
-
-
-
Indications d'application
- Western Blot: 1:500~1:1000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store antibody at -20°C for up to one year.
-
-
- VASP (Vasodilator-Stimulated phosphoprotein (VASP))
-
Autre désignation
- VASP
-
Sujet
- Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.
-
Poids moléculaire
- 50 kDa
-
ID gène
- 7408
-
NCBI Accession
- NP_003361
-
UniProt
- P50552
-
Pathways
- TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
Antigène
-