MAP2K5 anticorps (pSer311, pThr315)
Aperçu rapide pour MAP2K5 anticorps (pSer311, pThr315) (ABIN5689662)
Antigène
Voir toutes MAP2K5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer311, pThr315
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Specificité
- This antibody detects endogenous level of MEK5 only when phosphorylated at serine 311 or threonine 315.
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Purification
- Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
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Immunogène
- MEK5 (phospho-Ser311/ Thr315) antibody was raised against a peptide sequence around phosphorylation site of Serine 311 and threonine 315 (V-N-S (p) I-A-K-T (p) -Y-V) derived from Rat MEK5.
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Indications d'application
- Western Blot: 1:500~1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store antibody at -20°C for up to one year.
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- MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))
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Autre désignation
- MEK5
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Sujet
- Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appear to play a critical role in protecting cells from stress-induced apopotosis, neuronal survival and cardiac development and angiogenesis.
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Poids moléculaire
- 46 kDa
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ID gène
- 29568
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NCBI Accession
- NP_001029159
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UniProt
- Q62862
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Pathways
- Signalisation MAPK, Neurotrophin Signaling Pathway
Antigène
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