KDM1B anticorps (AA 80-130)

N° du produit ABIN5690029

L’anticorps Lapin Polyclonal anti-KDM1B a été validé pour ELISA et WB. Il convient pour détecter KDM1B dans des échantillons de Humain et Souris.

Aperçu rapide pour KDM1B anticorps (AA 80-130) (ABIN5690029)

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM1B est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-KDM1B anticorps

Épitope: AA 80-130

Specificité: KDM1B antibody is human, mouse and rat reactive. At least two isoforms of KDM1B are known to exist, this KDM1B antibody will detect both isoforms.

Purification: KDM1B antibody is affinity chromatography purified via peptide column.

Immunogène: KDM1B antibody was raised against a 17 amino acid peptide near the amino terminus of human KDM1B.

The immunogen is located within amino acids 80 - 130 of KDM1B.

Isotype: IgG

Information d'application

Indications d'application: KDM1B antibody can be used for detection of KDM1B by Western blot at 0.5 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KDM1B antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: KDM1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur KDM1B

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Autre désignation: KDM1B

Sujet: Flavin-dependent histone demethylases regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (reviewed in 1). KDM1B is a recently identified histone H3K4 demethylase that is required to establish maternal genomic imprints, targeted disruption of the KDM1B gene in mice led to lethality in their embryos, suggesting demethylation of H3K4 is critical for establishing the DNA methylation imprints (2). KDM1B has also been shown to play a role in the transcription elongation in several genes (3).

Poids moléculaire: Predicted: 90 kDa

Observed: 90 kDa

ID gène: 221656

NCBI Accession: NP_694587

UniProt: Q8NB78

Pathways: L'effet Warburg