KDM1B anticorps (N-Term)

N° du produit ABIN6972250

Cet anticorps anti-KDM1B Polyclonal Lapin (ABIN6972250) détecte spécifiquement KDM1B dans WB. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour KDM1B anticorps (N-Term) (ABIN6972250)

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDM1B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KDM1B anticorps

Épitope: N-Term

Attributs du produit: KDM1B / LSD2 (Lysine (K)-Specific Demethylase 1B / Lysine-Specific Histone Demethylase 2) is a histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4 (By similarity). KDM1B / LSD2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Mouse samples.

Purification: Affinity Purified

Immunogène: This antibody was raised against a peptide within the N-terminal region of mouse KDM1B / LSD2.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur KDM1B

Antigène: KDM1B (Lysine (K)-Specific Demethylase 1B (KDM1B))

Autre désignation: KDM1B / LSD2

Poids moléculaire: 93 kDa

NCBI Accession: NP_758466

Pathways: L'effet Warburg