Desmoplakin anticorps (AA 1810-2092)

N° du produit ABIN5693018

Détail du produit anti-Desmoplakin anticorps

Antigène: Desmoplakin (DSP)

Épitope: AA 1810-2092

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoplakin est non-conjugé

Application: ELISA, Western Blotting (WB)

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Desmoplakin detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogène: E. coli-derived human Desmoplakin recombinant protein (Position: Q1810-A2092).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Détails sur Desmoplakin

Antigène: Desmoplakin (DSP)

Autre désignation: DSP (DSP Produits)

Synonymes: anticorps DP, anticorps DPI, anticorps DPII, anticorps DSP, anticorps dpi, anticorps dpii, anticorps 2300002E22Rik, anticorps 5730453H04Rik, anticorps AA407887, anticorps AA407888, anticorps AW109828, anticorps im:6911953, anticorps sb:cb570, anticorps wu:fc17a08, anticorps wu:fk73d01, anticorps desmoplakin, anticorps Desmoplakin, anticorps ORF113, anticorps desmoplakin a, anticorps ORF112 DESMOPLAKIN, anticorps orf102, anticorps orf91; similar to Cydia pomonella granulovirus orf112, anticorps ORF62, anticorps ORF-66, anticorps ORF57, anticorps agip105, anticorps similar to XcORF133; similar to HaGV desmoplakin, anticorps desmoplakin L homeolog, anticorps ORF96, anticorps DSP, anticorps PhopGV104, anticorps ORF-59 desmoplakin, anticorps desmop, anticorps Dsp, anticorps dsp, anticorps desmoplakin, anticorps dspa, anticorps orf112 desmoplakin, anticorps ClgVgp102, anticorps COGV_gp091, anticorps APNV_p087, anticorps CBNV_gp066, anticorps EONV_gp057, anticorps OLNV_gp066, anticorps AgipMNPV_gp105, anticorps HaMNV_gp106, anticorps EupsNPV_gp065, anticorps PsunGV_gp139, anticorps dsp.L, anticorps ClanGV_gp096

Sujet:

Synonyms: Desmoplakin, DP, 250/210 kDa paraneoplastic pemphigus antigen, DSP

Tissue Specificity: Isoform DPI is apparently an obligate constituent of all desmosomes. Isoform DPII resides predominantly in tissues and cells of stratified origin.

Background: Desmoplakin is a protein in humans that is encoded by the DSP gene. This gene encodes a protein that anchors intermediate filaments to desmosomal plaques and forms an obligate component of functional desmosomes. Mutations in this gene are the cause of several cardiomyopathies and keratodermas, including skin fragility-woolly hair syndrome. Alternative splicing results in multiple transcript variants.

UniProt: P15924

Pathways: Cell-Cell Junction Organization