14-3-3 sigma/SFN anticorps (AA 1-248)

N° du produit ABIN5693156

Détail du produit anti-14-3-3 sigma/SFN anticorps

Antigène: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Épitope: AA 1-248

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 14-3-3 sigma/SFN est non-conjugé

Application: Western Blotting (WB), ELISA

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for 14-3-3 sigma detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogène: E. coli-derived human 14-3-3 sigma recombinant protein (Position: M1-S248).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-14-3-3 sigma/SFN (ABIN5693156)

Yang, Cheung, Peng, He, Wu, Xie, Jiang, Huang, Chen, Lin, Kung: "Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal." dans: The Journal of biological chemistry, Vol. 283, Issue 13, pp. 8486-95, (2008) (PubMed).

Détails sur 14-3-3 sigma/SFN

Antigène: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Autre désignation: SFN (SFN Produits)

Synonymes: anticorps YWHAS, anticorps Er, anticorps Mme1, anticorps Ywhas, anticorps stratifin, anticorps SFN, anticorps Sfn

Sujet:

Synonyms: 14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin, SFN, HME1

Tissue Specificity: Present mainly in tissues enriched in stratified squamous keratinizing epithelium.

Background: Stratifin(SFN), also known as 14-3-3 protein sigma, is strongly induced by gamma irradiation and other DNA-damaging agents. The induction of 14-3-3-sigma is mediated by a p53 -responsive element located 1.8 kb upstream of its transcription start site. The protein, called stratifin, was shown to be diffusely distributed in the cytoplasm and was present in cultured epithelial cells. It was most abundant in tissues enriched in stratified keratinizing epithelium.

UniProt: P31947

Pathways: Signalisation p53, Myometrial Relaxation and Contraction