eIF4EBP1 anticorps (AA 1-118)

N° du produit ABIN5696860

Cet anticorps Souris Monoclonal détecte spécifiquement eIF4EBP1 dans WB, IHC et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour eIF4EBP1 anticorps (AA 1-118) (ABIN5696860)

Antigène: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp eIF4EBP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-eIF4EBP1 anticorps

Épitope: AA 1-118

Fonction: EIF4EBP1 antibody

Immunogène:

Immunogen sequence: 1-118aa

Immunogen: eukaryotic translation initiation factor 4E binding protein 1

Isotype: IgG2b

Information d'application

Indications d'application: WB : 1:1000-1:10000,IHC : 1:20-1:200,IF : 1:20-1:200

Commentaires:

K-562 cells were subjected to SDS PAGE followed by western blot with FNab00006(4EBP1 antibody) at dilution of 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur eIF4EBP1

Antigène: eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

Autre désignation: EIF4EBP1

Sujet:

Synonyms: Eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1, eIF4E-binding protein 1)|Phosphorylated heat- and acid-stable protein regulated by insulin 1 (PHAS-I)|EIF4EBP1

Background: Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.

Poids moléculaire: 12kDa

UniProt: Q13541

Pathways: Signalisation MAPK, Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Regulation of Cell Size, BCR Signaling