IFNAR2 anticorps
Aperçu rapide pour IFNAR2 anticorps (ABIN5697945)
Antigène
Voir toutes IFNAR2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- IFNAR2 antibody
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Immunogène
- interferon (alpha, beta and omega) receptor 2
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
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Autre désignation
- IFNAR2
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Sujet
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Synonyms: Interferon alpha/beta receptor 2 (IFN-R-2, IFN-alpha binding protein, IFN-alpha/beta receptor 2)|Interferon alpha binding protein|Type I interferon receptor 2|IFNAR2|IFNABR|IFNARB
Background: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation(PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1(PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity(PubMed:7759950).
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Poids moléculaire
- 58-66 kDa
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ID gène
- 3455
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UniProt
- P48551
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Pathways
- Signalistation JAK/STAT, Hepatitis C
Antigène
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