alpha Adaptin anticorps

N° du produit ABIN5698814

L’anticorps Lapin Polyclonal anti-alpha Adaptin a été validé pour WB, IHC, ELISA, IP et IF. Il convient pour détecter alpha Adaptin dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour alpha Adaptin anticorps (ABIN5698814)

Antigène: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp alpha Adaptin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Détail du produit anti-alpha Adaptin anticorps

Fonction: AP2A1 antibody

Immunogène: adaptor-related protein complex 2, alpha 1 subunit

Isotype: IgG

Information d'application

Indications d'application: WB :1:500-1:5000,IP:1:500-1:5000,IHC:1:20-1:200,IF:1:10-1:100

Commentaires:

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00323(AP2A1 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur alpha Adaptin

Antigène: alpha Adaptin (AP2A1) (Adaptor-Related Protein Complex 2, alpha 1 Subunit (AP2A1))

Autre désignation: AP2A1

Sujet:

Synonyms: AP-2 complex subunit alpha-1|100 kDa coated vesicle protein A|Adaptor protein complex AP-2 subunit alpha-1|Adaptor-related protein complex 2 subunit alpha-1|Alpha-adaptin A|Alpha1-adaptin|Clathrin assembly protein complex 2 alpha-A large chain|Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit|AP2A1|ADTAA|CLAPA1

Background: This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.

Poids moléculaire: 108kDa

UniProt: O95782

Pathways: Signalisation Notch, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation