MYLK anticorps

N° du produit ABIN5699678

L’anticorps Lapin Polyclonal anti-MYLK a été validé pour WB, ELISA et IF. Il convient pour détecter MYLK dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MYLK anticorps (ABIN5699678)

Antigène: MYLK (Myosin Light Chain Kinase (MYLK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYLK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-MYLK anticorps

Fonction: MYLK antibody

Immunogène: myosin light chain kinase

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur MYLK

Antigène: MYLK (Myosin Light Chain Kinase (MYLK))

Autre désignation: MYLK

Sujet:

Synonyms: Myosin light chain kinase, smooth muscle (MLCK, smMLCK)|Kinase-related protein (KRP)|Telokin|Myosin light chain kinase, smooth muscle, deglutamylated form|MYLK|MLCK|MLCK1|MYLK1

Background: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.

Poids moléculaire: 135 kDa

ID gène: 4638

UniProt: Q15746