OGG1 anticorps

N° du produit ABIN5700181

Cet anticorps Lapin Polyclonal détecte spécifiquement OGG1 dans WB, IHC, ELISA et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour OGG1 anticorps (ABIN5700181)

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OGG1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Détail du produit anti-OGG1 anticorps

Fonction: OGG1 antibody

Immunogène: 8-oxoguanine DNA glycosylase

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab05980( OGG1 Antibody) at dilution of 1:600

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur OGG1

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Autre désignation: OGG1

Sujet:

Synonyms: N-glycosylase/DNA lyase|OGG1|MMH|MUTM|OGH1

Background: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.

Poids moléculaire: 47 kDa

ID gène: 4968

UniProt: O15527

Pathways: Réparation de l'ADN