CD3D anticorps (AA 22-171)

N° du produit ABIN5701788

Cet anticorps anti-CD3D est un anticorps Lapin Polyclonal détectant CD3D dans WB, IHC, ELISA et FACS. Adapté pour Humain et Souris.

Aperçu rapide pour CD3D anticorps (AA 22-171) (ABIN5701788)

Antigène: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD3D est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Détail du produit anti-CD3D anticorps

Épitope: AA 22-171

Fonction: CD3D antibody

Immunogène:

Immunogen sequence: 22-171aa

Immunogen: CD3d molecule, delta (CD3-TCR complex)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab01456(CD3D antibody) at dilution of 1:800

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur CD3D

Antigène: CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))

Autre désignation: CD3D

Sujet:

Synonyms: T-cell surface glycoprotein CD3 delta chain|T-cell receptor T3 delta chain|CD3D|T3D

Background: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

Poids moléculaire: 20-25 kDa

Pathways: TCR Signaling, CXCR4-mediated Signaling Events