RENT1/UPF1 anticorps

N° du produit ABIN5704268

L’anticorps anti-RENT1/UPF1 Polyclonal produit chez le Lapin a été validé pour WB, IHC, ELISA, IF et IP. Il convient pour la détection de RENT1/UPF1 dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour RENT1/UPF1 anticorps (ABIN5704268)

Antigène: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RENT1/UPF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-RENT1/UPF1 anticorps

Fonction: UPF1 antibody

Immunogène: UPF1 regulator of nonsense transcripts homolog (yeast)

Isotype: IgG

Information d'application

Indications d'application: WB : 1:500-1:5000,IHC:1:20-1:200,IF:1:20-1:200,IP:1:200-1:2000

Commentaires:

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09270(UPF1 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RENT1/UPF1

Antigène: RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))

Autre désignation: UPF1

Sujet:

Synonyms: Regulator of nonsense transcripts 1|ATP-dependent helicase RENT1|Nonsense mRNA reducing factor 1 (NORF1)|Up-frameshift suppressor 1 homolog (hUpf1)|UPF1|KIAA0221|RENT1

Background: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 43kDa

ID gène: 5976

UniProt: Q92900

Pathways: SARS-CoV-2 Protein Interactome