PDE9A anticorps

N° du produit ABIN5705074

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE9A dans ELISA, WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PDE9A anticorps (ABIN5705074)

Antigène: PDE9A (phosphodiesterase 9A (PDE9A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE9A est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PDE9A anticorps

Fonction: PDE9A antibody

Immunogène: phosphodiesterase 9A

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab06263( PDE9A Antibody) at dilution of 1:300

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PDE9A

Antigène: PDE9A (phosphodiesterase 9A (PDE9A))

Autre désignation: PDE9A

Sujet:

Synonyms: High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A|PDE9A

Background: Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP(PubMed:9624146, PubMed:18757755, PubMed:21483814). Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart(PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein(Probable). In brain, involved in cognitive function, such as learning and long-term memory(By similarity).

ID gène: 5152

UniProt: O76083