ORAI1 anticorps

N° du produit ABIN5706864

N° du produit (Fournisseur): 100-401-p17

Cet anticorps anti-ORAI1 est un anticorps Lapin Polyclonal détectant ORAI1 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour ORAI1 anticorps (ABIN5706864)

Antigène: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ORAI1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ORAI1 anticorps

N° du produit (Fournisseur): 100-401-p17

Fournisseur: Rockland

Fonction: ORAI1 Antibody

Réactivité croisée (Details): Anti-ORAI-1 antibody is directed against the human ORAI-1.

Attributs du produit: Synonyms: rabbit anti-ORAI-1 Antibody, Calcium release-activated calcium channel protein 1, orai-1, Transmembrane protein 142A, ORAI1, CRACM1, TMEM142A

Purification: The product was prepared from monospecific antiserum by delipidation and defibrination.

Stérilité: Sterile filtered

Immunogène:

Immunogen: This whole rabbit serum was prepared by repeated immunizations with a recombinant fusion protein.

Immunogen Type: Recombinant Protein

Isotype: IgG

Information d'application

Indications d'application:

Application Note: Anti-ORAI-1 has been tested for use in western blotting. Specific conditions for reactivity should be optimized by the end user. Expect bands approximately 32.7 kDa by western blotting in the appropriate cell lysate or extract.

Western Blot Dilution: 1.0 μg/mL

ELISA Dilution: 1.0 μg/well

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur ORAI1

Antigène: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Autre désignation: ORAI1

Sujet: Background: The ORAI-1 gene codes for the calcium release-activated calcium (CRAC) channel subunit in humans. The CRAC channel subunit mediates calcium influx when activated by the calcium sensor, STIM1, following depletion of intracellular calcium stores. CRAC channels are the primary pathway for calcium influx in T-cells and promote the immune response to pathogens through activation of the transcription factor NFAT. Defects in this gene can be a cause of immune dysfunction due to inactivation of T-cells.

ID gène: 84876

NCBI Accession: NP_116179

UniProt: Q96D31

Pathways: TCR Signaling, BCR Signaling