E2F1 anticorps (Internal Region, Lys120)

N° du produit ABIN571306

Cet anticorps anti-E2F1 est un anticorps Lapin Polyclonal détectant E2F1 dans WB, ELISA et IHC. Adapté pour Humain et Souris.

Aperçu rapide pour E2F1 anticorps (Internal Region, Lys120) (ABIN571306)

Antigène: E2F1 (E2F Transcription Factor 1 (E2F1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp E2F1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-E2F1 anticorps

Épitope: Internal Region, Lys120

Specificité: Reacts with human E2F-1 acK120 and acK125

Réactivité croisée: Souris

Réactivité croisée (Details): May cross-react with E2F-1 from mouse and other species due to sequence homology

Purification: Antiserum

Immunogène: Synthetic peptide derived from internal domain of human E2F-1 protein containing acetyl lysine 120 and 125

Isotype: IgG

Information d'application

Indications d'application:

Working dilution: Optimal dilutions should be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur E2F1

Antigène: E2F1 (E2F Transcription Factor 1 (E2F1))

Autre désignation: Transcription Factor E2F1 (E2F-1)

Sujet: Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.

UniProt: Q01094

Pathways: Signalisation p53, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy