E2F1 anticorps (Internal Region, Lys120)
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- Antigène Voir toutes E2F1 Anticorps
- E2F1 (E2F Transcription Factor 1 (E2F1))
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Épitope
- Internal Region, Lys120
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp E2F1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificité
- Reacts with human E2F-1 acK120 and acK125
- Réactivité croisée
- Souris
- Réactivité croisée (Details)
- May cross-react with E2F-1 from mouse and other species due to sequence homology
- Purification
- Antiserum
- Immunogène
- Synthetic peptide derived from internal domain of human E2F-1 protein containing acetyl lysine 120 and 125
- Isotype
- IgG
- Top Product
- Discover our top product E2F1 Anticorps primaire
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- Indications d'application
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Working dilution: Optimal dilutions should be determined by the end user.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Date de péremption
- 24 months
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- Antigène
- E2F1 (E2F Transcription Factor 1 (E2F1))
- Autre désignation
- Transcription Factor E2F1 (E2F-1) (E2F1 Produits)
- Synonymes
- anticorps CG6376, anticorps DRTF1/E2F, anticorps DmE2F-1, anticorps Dmel\\CG6376, anticorps Dp, anticorps E(Sev-CycE)3A, anticorps E(var)3-93E, anticorps E(var)3-95E, anticorps E(var)93E, anticorps E2F, anticorps E2F-1, anticorps E2F1, anticorps E2f1, anticorps Evar(3)164, anticorps dE2F, anticorps dE2F1, anticorps dE2f, anticorps dE2f1, anticorps de2f1, anticorps def21, anticorps drosE2F1, anticorps e2f, anticorps e2f1, anticorps l(3)07172, anticorps l(3)j3B1, anticorps l(3)j3C2, anticorps l(3)rM729, anticorps RBAP1, anticorps RBBP3, anticorps RBP3, anticorps mKIAA4009, anticorps xE2F, anticorps ATE2FB, anticorps E2F TRANSCRIPTION FACTOR-1 E2F1, anticorps E2F transcription factor 1, anticorps E2FB, anticorps E2FB TRANSCRIPTION FACTOR, anticorps E2F transcription factor 1, anticorps E2F transcription factor 1 L homeolog, anticorps E2f1, anticorps E2F1, anticorps e2f1.L
- Sujet
- Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis.
- UniProt
- Q01094
- Pathways
- Signalisation p53, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
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