PRKDC anticorps

N° du produit ABIN576237

Cet anticorps anti-PRKDC est un anticorps Lapin Polyclonal détectant PRKDC dans WB, IHC, IP, IHC (p) et GS. Adapté pour Humain, Souris, Rat et Hamster.

Aperçu rapide pour PRKDC anticorps (ABIN576237)

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Reactivité: Humain, Souris, Rat, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKDC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Gel Shift (GS)

Détail du produit anti-PRKDC anticorps

Specificité: Recognizes the human DNA-dependent protein kinase catalytic subunit, also known as DNA-PKcs, DNPK1 or p460. DNA PKcs is a 4128 amino acid ~460 kD nuclear protein encoded by the PRKDC gene, acting as a molecular sensor for DNA damage. Mutation of the PRKDC gene can result in Immunodeficiency 26 with or without neurologic abnormalities.

Immunogène: Human DNA-PKcs fragment.

Isotype: IgG

Information d'application

Indications d'application: Approved: GS, IHC, IHC-P (1:100), IP, WB (1:2000)

Usage: Immunohistology: This product requires heat mediated treatment of paraffin sections. We recommend the use of antigen unmasking fluid for this purpose. A two hour incubation with LS-C42724 is recommended.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Serum, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur PRKDC

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Autre désignation: PRKDC / DNA-PKcs

Sujet: Name/Gene ID: PRKDC
Subfamily: PI3/PI4
Family: Protein Kinase

Synonyms: PRKDC, DNA-PK, DNAPK, DNPK1, HYRC, HYRC1, p350, Scid, XRCC7, DNA-PK catalytic subunit, DNA-PKcs, p460, DNA-dependent protein kinase catalytic subunit

ID gène: 5591

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response