PRKDC anticorps

N° du produit ABIN576237

Cet anticorps anti-PRKDC Polyclonal Lapin (ABIN576237) détecte spécifiquement PRKDC dans WB, IHC, IP, IHC (p) et GS. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Hamster.

Aperçu rapide pour PRKDC anticorps (ABIN576237)

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Reactivité: Humain, Souris, Rat, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKDC est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Gel Shift (GS)

Détail du produit anti-PRKDC anticorps

Specificité: Recognizes the human DNA-dependent protein kinase catalytic subunit, also known as DNA-PKcs, DNPK1 or p460. DNA PKcs is a 4128 amino acid ~460 kD nuclear protein encoded by the PRKDC gene, acting as a molecular sensor for DNA damage. Mutation of the PRKDC gene can result in Immunodeficiency 26 with or without neurologic abnormalities.

Immunogène: Human DNA-PKcs fragment.

Isotype: IgG

Information d'application

Indications d'application: Approved: GS, IHC, IHC-P (1:100), IP, WB (1:2000)

Usage: Immunohistology: This product requires heat mediated treatment of paraffin sections. We recommend the use of antigen unmasking fluid for this purpose. A two hour incubation with LS-C42724 is recommended.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Serum, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur PRKDC

Antigène: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Autre désignation: PRKDC / DNA-PKcs

Sujet: Name/Gene ID: PRKDC
Subfamily: PI3/PI4
Family: Protein Kinase

Synonyms: PRKDC, DNA-PK, DNAPK, DNPK1, HYRC, HYRC1, p350, Scid, XRCC7, DNA-PK catalytic subunit, DNA-PKcs, p460, DNA-dependent protein kinase catalytic subunit

ID gène: 5591

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response