Integrin beta 2 anticorps (PE)

N° du produit ABIN576530

Détail du produit anti-Integrin beta 2 anticorps (PE)

Antigène: Integrin beta 2 (ITGB2)

Reactivité: Humain, Chien

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 2 est conjugé à/à la PE

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

Specificité: YFC118.3 was clustered at the Fourth International Workshop on Leucocyte Differentiation Antigen (code number N221) as recognizing the CD18 antigen. The CD18 antigen is an integral membrane glycoprotein of 95kD molecular weight - known as the b chain, of the LFA-1 complex. The CD18 antigen is non-covalently linked to CD11a, b, c molecules. The main cellular reactivity of antibody YFC 118.3 is a strong reactivity with Leucocytes (platelets negative). The CD18 Molecule is the receptor for ICAM-1 and is thus important for cell adhesion. YFC118.3 blocks homotypic adhesion and other lymphocyte functions which involve the LFA-1 antigen.

Purification: Protein G purified

Immunogène: Human neutrophils.

Type of Immunogen: Cells

Isotype: IgG2b

Information d'application

Indications d'application: Approved: Block, Flo (1:1), IHC, IHC-Fr, IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 100 μL whole blood or 10^6 cells in 100 μL. Method sheets are available on request.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Distilled Water.

Concentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.2, 0.09 % sodium azide, 1 % BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur Integrin beta 2

Antigène: Integrin beta 2 (ITGB2)

Autre désignation: ITGB2 / MAC-1 / CD18 (ITGB2 Produits)

Synonymes: anticorps CD18, anticorps LAD, anticorps LCAMB, anticorps LFA-1, anticorps MAC-1, anticorps MF17, anticorps MFI7, anticorps 2E6, anticorps AI528527, anticorps Cd18, anticorps Lfa1, anticorps ITGB2, anticorps itgb2, anticorps itgb2-a, anticorps itgb2-b, anticorps integrin subunit beta 2, anticorps integrin beta 2, anticorps integrin subunit beta 2 S homeolog, anticorps ITGB2, anticorps Itgb2, anticorps itgb2.S

Sujet: Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

ID gène: 3689

UniProt: P05107

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation