Layilin anticorps (AA 22-235)

N° du produit ABIN5775959

Cet anticorps anti-Layilin est un anticorps Souris Monoclonal détectant Layilin dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour Layilin anticorps (AA 22-235) (ABIN5775959)

Antigène: Layilin (LAYN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Layilin est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: AT18E10

Détail du produit anti-Layilin anticorps

Épitope: AA 22-235

Fonction: Human Layilin/LAYN antibody

Purification: Purified

Immunogène: Recombinant human LAYN (22-235aa) purified from E. coli

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détails sur Layilin

Antigène: Layilin (LAYN)

Autre désignation: Layilin/LAYN

Sujet: Layilin is a widely expressed integral membrane hyaluronan receptor and a transmembrane protein with homology to C-type lectins. This protein interacts with the ERM protein family of cytoskeletal membrane linker molecule members, including talin, ezrin, moesin, and radixin. The carboxy-terminal domain of layilin is capable of binding to the amino-terminal domain of radixin. An interdomain interaction between the amino- and the carboxy-terminal domains of radixin inhibits its ability to bind to layilin. Layilin plays an important role in cell adhesion and motility. It is important for the maintenance of the cortical structure in the cell because it mediates signals from the extracellular matrix to the cytoskeleton. In spreading cells, Layilin acts as a membrane-binding site for talin in the peripheral ruffles, and it may play a role in the migration of cells to a wound site.

NCBI Accession: NP_001245319