TDP1 anticorps (AA 1-298)
Aperçu rapide pour TDP1 anticorps (AA 1-298) (ABIN5775991)
Antigène
Voir toutes TDP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 1-298
-
Fonction
- Human TDP1 antibody
-
Purification
- Purified
-
Immunogène
- Recombinant human TDP1 (1-298aa) purified from E. coli
-
Isotype
- IgG2b kappa
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C,-80 °C
-
Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
-
-
- TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
-
Autre désignation
- TDP1
-
Sujet
- Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate. This protein is a member of the phospholipase D (PLD) superfamily and contains two PLD phosphodiesterase domains. Mutations in TDP1 are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1) by interfering with DNA transcription or by inducting apoptosis in postmitotic neurons.
-
NCBI Accession
- NP_060789
Antigène
-