DNMT3B anticorps

N° du produit ABIN5959392

L’anticorps Lapin Polyclonal anti-DNMT3B a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter DNMT3B dans des échantillons de Humain et Poulet.

Aperçu rapide pour DNMT3B anticorps (ABIN5959392)

Antigène: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Reactivité: Humain, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNMT3B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-DNMT3B anticorps

Specificité: Cytosine 5methyltransferase 3B,DNA,DNA (cytosine 5) methyltransferase 3 beta,DNA (cytosine 5)-methyltransferase 3B,DNA (cytosine-5)-methyltransferase 3B,DNA methyltransferase HsaIIIB,DNA MTase HsaIIIB,DNM3B,Dnmt3b,EC 2.1.1.37,ICF,ICF1,M.HsaIIIB,MGC124407,RP23-89H14.3

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the N-terminal region of human Dnmt3b

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DNMT3B

Antigène: DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

Autre désignation: Dnmt3b

Sujet: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Poids moléculaire: 96kDa

ID gène: 1789

UniProt: Q9UBC3