EIF2S1 anticorps (pSer51)

N° du produit ABIN6136058

Cet anticorps Lapin Polyclonal détecte spécifiquement EIF2S1 dans WB, IHC et IP. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour EIF2S1 anticorps (pSer51) (ABIN6136058)

Antigène: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF2S1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-EIF2S1 anticorps

Épitope: pSer51

Séquence: SELSR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Phosphorylated Antibodies

Purification: Affinity purification

Immunogène: A synthetic phosphorylated peptide around S51 of human eIF2alpha (NP_004085.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EIF2S1

Antigène: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Autre désignation: EIF2S1

Sujet: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2, MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],EIF-2,EIF-2A,EIF-2alpha,EIF2,EIF2A,EIF2S1,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,Regulation of eIF2,Cell Biology & Developmental Biology,Protein folding,Protein phosphorylation,EIF2S1

Poids moléculaire: 36 kDa

ID gène: 1965

UniProt: P05198

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C