BBS10 anticorps (AA 474-723)

N° du produit ABIN6137466

Cet anticorps Lapin Polyclonal détecte spécifiquement BBS10 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour BBS10 anticorps (AA 474-723) (ABIN6137466)

Antigène: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BBS10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BBS10 anticorps

Épitope: AA 474-723

Séquence: AENKDALEKT QTYLKVHSNL VIPDVELETY IPYSTPTLTP TDTFQTVETL TCLSLERNRL TDYYEPLLKN NSTAYSTRGN RIEISYENLQ VTNITRKGSM LPVSCKLPNM GTSQSYLSSS MPAGCVLPVG GNFEILLHYY LLNYAKKCHQ SEETMVSMII ANALLGIPKV LYKSKTGKYS FPHTYIRAVH ALQTNQPLVS SQTGLESVMG KYQLLTSVLQ CLTKILTIDM VITVKRHPQK VHNQDSEDEL

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 474-723 of human BBS10 (NP_078961.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:3000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BBS10

Antigène: BBS10 (Bardet-Biedl Syndrome 10 (BBS10))

Autre désignation: BBS10

Sujet: This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.,BBS10,C12orf58,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,BBS10

Poids moléculaire: 80 kDa

ID gène: 79738

UniProt: Q8TAM1