Cet anticorps anti-C5AR1 Polyclonal Lapin (ABIN6137777) détecte spécifiquement C5AR1 dans WB et IHC.
L’anticorps est réactif avec des échantillons de Humain.
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.,C5AR1,C5A,C5AR,C5R1,CD88,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,C5AR1