Caspase 2 anticorps (AA 153-452)
Aperçu rapide pour Caspase 2 anticorps (AA 153-452) (ABIN6137960)
Antigène
Voir toutes Caspase 2 (CASP2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 153-452
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Séquence
- KLRLSTDTVE HSLDNKDGPV CLQVKPCTPE FYQTHFQLAY RLQSRPRGLA LVLSNVHFTG EKELEFRSGG DVDHSTLVTL FKLLGYDVHV LCDQTAQEMQ EKLQNFAQLP AHRVTDSCIV ALLSHGVEGA IYGVDGKLLQ LQEVFQLFDN ANCPSLQNKP KMFFIQACRG DETDRGVDQQ DGKNHAGSPG CEESDAGKEK LPKMRLPTRS DMICGYACLK GTAAMRNTKR GSWYIEALAQ VFSERACDMH VADMLVKVNA LIKDREGYAP GTEFHRCKEM SEYCSTLCRH LYLFPGHPPT
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 153-452 of human Caspase-2 (NP_116764.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
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Autre désignation
- CASP2
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Sujet
- This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,CASP2,CASP-2,ICH1,NEDD-2,NEDD2,PPP1R57,caspase-2,Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Mitochondrial Control of Apoptosis,Ubiquitin,Endocrine & Metabolism,Immunology & Inflammation,CASP2
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Poids moléculaire
- 10 kDa/34 kDa/50 kDa
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ID gène
- 835
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UniProt
- P42575
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
Antigène
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