Cyclin D3 anticorps (AA 201-292)

N° du produit ABIN6138087

Cet anticorps Lapin Polyclonal détecte spécifiquement Cyclin D3 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour Cyclin D3 anticorps (AA 201-292) (ABIN6138087)

Antigène: Cyclin D3 (CCND3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin D3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Cyclin D3 anticorps

Épitope: AA 201-292

Séquence: SMIATGSIGA AVQGLGACSM SGDELTELLA GITGTEVDCL RACQEQIEAA LRESLREASQ TSSSPAPKAP RGSSSQGPSQ TSTPTDVTAI HL

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 201-292 of human Cyclin D3 (NP_001751.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Cyclin D3

Antigène: Cyclin D3 (CCND3)

Autre désignation: CCND3

Sujet: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.,CCND3,cyclin D3,Cyclin D3,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cyclins,G1/S Checkpoint,Hedgehog Signaling Pathway,CCND3

Poids moléculaire: 9 kDa/22 kDa/24 kDa/32 kDa

ID gène: 896

UniProt: P30281

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process