Dopamine d2 Receptor anticorps (AA 214-373)

N° du produit ABIN6139821

Cet anticorps anti-Dopamine d2 Receptor est un anticorps Lapin Polyclonal détectant Dopamine d2 Receptor dans WB. Adapté pour Humain.

Aperçu rapide pour Dopamine d2 Receptor anticorps (AA 214-373) (ABIN6139821)

Antigène: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dopamine d2 Receptor est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Dopamine d2 Receptor anticorps

Épitope: AA 214-373

Séquence: IVLRRRRKRV NTKRSSRAFR AHLRAPLKGN CTHPEDMKLC TVIMKSNGSF PVNRRRVEAA RRAQELEMEM LSSTSPPERT RYSPIPPSHH QLTLPDPSHH GLHSTPDSPA KPEKNGHAKD HPKIAKIFEI QTMPNGKTRT SLKTMSRRKL SQQKEKKATQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 214-373 of human DRD2 (NP_000786.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Dopamine d2 Receptor

Antigène: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Autre désignation: DRD2

Sujet: This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia, other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.,DRD2,D2DR,D2R,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Neuron marker,Dendrite marker,DRD2

Poids moléculaire: 47 kDa/50 kDa

ID gène: 1813

UniProt: P14416

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity