FDPS anticorps (AA 120-419)
Aperçu rapide pour FDPS anticorps (AA 120-419) (ABIN6140569)
Antigène
Voir toutes FDPS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 120-419
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Séquence
- IGGKYNRGLT VVVAFRELVE PRKQDADSLQ RAWTVGWCVE LLQAFFLVAD DIMDSSLTRR GQICWYQKPG VGLDAINDAN LLEACIYRLL KLYCREQPYY LNLIELFLQS SYQTEIGQTL DLLTAPQGNV DLVRFTEKRY KSIVKYKTAF YSFYLPIAAA MYMAGIDGEK EHANAKKILL EMGEFFQIQD DYLDLFGDPS VTGKIGTDIQ DNKCSWLVVQ CLQRATPEQY QILKENYGQK EAEKVARVKA LYEELDLPAV FLQYEEDSYS HIMALIEQYA APLPPAVFLG LARKIYKRRK
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 120-419 of human FDPS (NP_001129293.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- FDPS (Farnesyl Diphosphate Synthase (FDPS))
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Autre désignation
- FDPS
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Sujet
- This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.,FDPS,FPPS,FPS,POROK9,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Tumor biomarkers,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Lipids,FDPS
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Poids moléculaire
- 40 kDa/48 kDa
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ID gène
- 2224
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UniProt
- P14324
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Pathways
- Regulation of Muscle Cell Differentiation
Antigène
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