FZD6 anticorps (AA 19-201)

N° du produit ABIN6140848

Cet anticorps anti-FZD6 est un anticorps Lapin Polyclonal détectant FZD6 dans WB et IHC. Adapté pour Humain.

Aperçu rapide pour FZD6 anticorps (AA 19-201) (ABIN6140848)

Antigène: FZD6 (Frizzled Family Receptor 6 (FZD6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FZD6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-FZD6 anticorps

Épitope: AA 19-201

Séquence: HSLFTCEPIT VPRCMKMAYN MTFFPNLMGH YDQSIAAVEM EHFLPLANLE CSPNIETFLC KAFVPTCIEQ IHVVPPCRKL CEKVYSDCKK LIDTFGIRWP EELECDRLQY CDETVPVTFD PHTEFLGPQK KTEQVQRDIG FWCPRHLKTS GGQGYKFLGI DQCAPPCPNM YFKSDELEFA KSF

Réactivité croisée: Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 19-201 of human FZD6 (NP_003497.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:1000 - 1:2000,IHC,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur FZD6

Antigène: FZD6 (Frizzled Family Receptor 6 (FZD6))

Autre désignation: FZD6

Sujet: This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.,FZD6,FZ-6,FZ6,HFZ6,NDNC10,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),mTOR Signaling Pathway,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Stem Cells,FZD6

Poids moléculaire: 75 kDa/79 kDa

ID gène: 8323

UniProt: O60353

Pathways: Signalisation WNT, Tube Formation