GBA anticorps (AA 40-250)

N° du produit ABIN6140986

Cet anticorps anti-GBA est un anticorps Lapin Polyclonal détectant GBA dans WB. Adapté pour Humain.

Aperçu rapide pour GBA anticorps (AA 40-250) (ABIN6140986)

Antigène: GBA (Glucosidase, Beta, Acid (GBA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GBA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GBA anticorps

Épitope: AA 40-250

Séquence: ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT FPALGTFSRY ESTRSGRRME LSMGPIQANH TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA LNILALSPPA QNLLLKSYFS EEGIGYNIIR VPMASCDFSI RTYTYADTPD DFQLHNFSLP EEDTKLKIPL IHRALQLAQR PVSLLASPWT SPTWLKTNGA VNGKGSLKGQ PGDIYHQTWA R

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human Glucosylceramidase beta (Glucosylceramidase beta (GBA)) (NP_000148.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur GBA

Antigène: GBA (Glucosidase, Beta, Acid (GBA))

Autre désignation: GBA

Sujet: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.,GBA,GBA1,GCB,GLUC,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Dopamine Signaling in Parkinson's Disease,Oligodendrocyte marker,GBA

Poids moléculaire: 29 kDa/50 kDa/54 kDa/57 kDa/59 kDa

ID gène: 2629

UniProt: P04062

Pathways: Cellular Glucan Metabolic Process