Glypican 3 anticorps (AA 290-550)

N° du produit ABIN6141306

L’anticorps Lapin Polyclonal anti-Glypican 3 a été validé pour IF et WB. Il convient pour détecter Glypican 3 dans des échantillons de Humain.

Aperçu rapide pour Glypican 3 anticorps (AA 290-550) (ABIN6141306)

Antigène: Glypican 3 (GPC3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glypican 3 est non-conjugé

Application: Immunofluorescence (IF), Western Blotting (WB)

Détail du produit anti-Glypican 3 anticorps

Épitope: AA 290-550

Séquence: VEIDKYWREY ILSLEELVNG MYRIYDMENV LLGLFSTIHD SIQYVQKNAG KLTTTIGKLC AHSQQRQYRS AYYPEDLFID KKVLKVAHVE HEETLSSRRR ELIQKLKSFI SFYSALPGYI CSHSPVAEND TLCWNGQELV ERYSQKAARN GMKNQFNLHE LKMKGPEPVV SQIIDKLKHI NQLLRTMSMP KGRVLDKNLD EEGFESGDCG DDEDECIGGS GDGMIKVKNQ LRFLAELAYD LDVDDAPGNS QQATPKDNEI S

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 290-550 of human Glypican 3 (GPC3) (GPC3) (NP_004475.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Glypican 3

Antigène: Glypican 3 (GPC3)

Autre désignation: GPC3

Sujet: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.,GPC3,DGSX,GTR2-2,MXR7,OCI-5,SDYS,SGB,SGBS,SGBS1,glypican-3,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Stem Cells,GPC3

Poids moléculaire: 59 kDa/65 kDa/68 kDa

ID gène: 2719

UniProt: P51654

Pathways: Glycosaminoglycan Metabolic Process