Metabotropic Glutamate Receptor 1 anticorps (AA 920-1140)

N° du produit ABIN6141420

L’anticorps Lapin Polyclonal anti-Metabotropic Glutamate Receptor 1 a été validé pour WB. Il convient pour détecter Metabotropic Glutamate Receptor 1 dans des échantillons de Humain.

Aperçu rapide pour Metabotropic Glutamate Receptor 1 anticorps (AA 920-1140) (ABIN6141420)

Antigène: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Metabotropic Glutamate Receptor 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Metabotropic Glutamate Receptor 1 anticorps

Épitope: AA 920-1140

Séquence: NETACNQTAV IKPLTKSYQG SGKSLTFSDT STKTLYNVEE EEDAQPIRFS PPGSPSMVVH RRVPSAATTP PLPSHLTAEE TPLFLAEPAL PKGLPPPLQQ QQQPPPQQKS LMDQLQGVVS NFSTAIPDFH AVLAGPGGPG NGLRSLYPPP PPPQHLQMLP LQLSTFGEEL VSPPADDDDD SERFKLLQEY VYEHEREGNT EEDELEEEEE DLQAASKLTP D

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 920-1140 of human GRM1 (NP_000829.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Metabotropic Glutamate Receptor 1

Antigène: Metabotropic Glutamate Receptor 1 (GRM1) (Glutamate Receptor, Metabotropic 1 (GRM1))

Autre désignation: GRM1

Sujet: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.,GRM1,GPRC1A,MGLU1,MGLUR1,PPP1R85,SCAR13,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,GRM1

Poids moléculaire: 101 kDa/132 kDa

ID gène: 2911

UniProt: Q13255