IRS2 anticorps (AA 510-650)

N° du produit ABIN6142544

Cet anticorps Lapin Polyclonal détecte spécifiquement IRS2 dans WB et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour IRS2 anticorps (AA 510-650) (ABIN6142544)

Antigène: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRS2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-IRS2 anticorps

Épitope: AA 510-650

Séquence: LRAFCSHRSN TPESIAETPP ARDGGGGGEF YGYMTMDRPL SHCGRSYRRV SGDAAQDLDR GLRKRTYSLT TPARQRPVPQ PSSASLDEYT LMRATFSGSA GRLCPSCPAS SPKVAYHPYP EDYGDIEIGS HRSSSSNLGA D

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 510-650 of human IRS2 (NP_003740.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IRS2

Antigène: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Autre désignation: IRS2

Sujet: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.,IRS2,IRS-2,Cancer,Signal Transduction,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Immunology & Inflammation,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,IRS2

Poids moléculaire: 137 kDa

ID gène: 8660

UniProt: Q9Y4H2

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process