KIT anticorps (AA 25-295)
Aperçu rapide pour KIT anticorps (AA 25-295) (ABIN6142896)
Antigène
Voir toutes KIT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 25-295
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Séquence
- SQPSVSPGEP SPPSIHPGKS DLIVRVGDEI RLLCTDPGFV KWTFEILDET NENKQNEWIT EKAEATNTGK YTCTNKHGLS NSIYVFVRDP AKLFLVDRSL YGKEDNDTLV RCPLTDPEVT NYSLKGCQGK PLPKDLRFIP DPKAGIMIKS VKRAYHRLCL HCSVDQEGKS VLSEKFILKV RPAFKAVPVV SVSKASYLLR EGEEFTVTCT IKDVSSSVYS TWKRENSQTK LQEKYNSWHH GDFNYERQAT LTISSARVND SGVFMCYANN T
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 25-295 of human CD117/c-Kit (NP_000213.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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Autre désignation
- KIT
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Sujet
- This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.,KIT,C-Kit,CD117,PBT,SCFR,c-kit,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,CD markers,Cytokines,Neuroscience,Cell Type Marker,Stem Cells,Germline Stem Cells,Hematopoietic Progenitors,KIT
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Poids moléculaire
- 46 kDa/109 kDa
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ID gène
- 3815
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UniProt
- P10721
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
Antigène
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