LIFR anticorps (AA 500-700)

N° du produit ABIN6143204

Détail du produit anti-LIFR anticorps

Antigène: LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

Épitope: AA 500-700

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIFR est non-conjugé

Application: Western Blotting (WB)

Séquence: NPYTLYTFRI RCSTETFWKW SKWSNKKQHL TTEASPSKGP DTWREWSSDG KNLIIYWKPL PINEANGKIL SYNVSCSSDE ETQSLSEIPD PQHKAEIRLD KNDYIISVVA KNSVGSSPPS KIASMEIPND DLKIEQVVGM GKGILLTWHY DPNMTCDYVI KWCNSSRSEP CLMDWRKVPS NSTETVIESD EFRPGIRYNF F

Réactivité croisée: Souris

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human LIFR (NP_002301.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LIFR

Antigène: LIFR (Leukemia Inhibitory Factor Receptor alpha (LIFR))

Autre désignation: LIFR (LIFR Produits)

Synonymes: anticorps A230075M04Rik, anticorps AW061234, anticorps LIF, anticorps CD118, anticorps LIF-R, anticorps SJS2, anticorps STWS, anticorps SWS, anticorps leukemia inhibitory factor receptor, anticorps LIF receptor alpha, anticorps leukemia inhibitory factor receptor alpha, anticorps Lifr, anticorps LOC397451, anticorps LIFR

Sujet: This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5,8)(p13,q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.,LIFR,CD118,LIF-R,SJS2,STWS,SWS,Cell Biology & Developmental Biology,Immunology & Inflammation,CD markers,Cytokines,Cell Intrinsic Innate Immunity Signaling Pathway,Stem Cells,Embryonic Stem Cells,LIFR

Poids moléculaire: 123 kDa

ID gène: 3977

UniProt: P42702

Pathways: Signalistation JAK/STAT, Growth Factor Binding