Caspase 7 anticorps

N° du produit ABIN614356

Cet anticorps Souris Monoclonal détecte spécifiquement Caspase 7 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Singe, Porc, Chien, Lapin, Hamster et Mouton.

Aperçu rapide pour Caspase 7 anticorps (ABIN614356)

Antigène: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reactivité: Humain, Souris, Rat, Singe, Porc, Chien, Lapin, Hamster, Mouton

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Caspase 7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 07-01-11

Détail du produit anti-Caspase 7 anticorps

Specificité: Detects an ~37 kDa protein, corresponding to the apparent molecular mass of the Caspase-7 on SDS-PAGE Immunoblots, in samples from Human, Mouse, Rat, Monkey, Dog, Sheep, Rabbit, Pig and Hamster origins. This antibody recognizes the unprocessed pro-caspase-7 (p35), caspase-7 lacking the short amino- terminal pro domain (32 kDa) and the fully processed Caspase-7 (p19) in apoptotic cell extracts.

Réactivité croisée (Details): Species reactivity (expected):Canine, Hamster, Monkey, Mouse, Porcine, Rabbit, Rat, Sheep.
Species reactivity (tested):Human.

Purification: Protein G Chromatography.

Immunogène: Recombinant Human CASP7.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.4 mg/mL

Buffer: 10 mM Sodium Phosphate, pH 7.2, 50 mM Sodium Chloride with 0.1 mM PMSF

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Caspase 7

Antigène: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Autre désignation: Caspase-7

Sujet: Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis, initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase 3 and Caspase 7, which in turn cause cell collapse.Synonyms: Apoptotic protease Mch-3, CASP-7, CASP7, CMH-1, ICE-like apoptotic protease 3, MCH3

ID gène: 840

NCBI Accession: NP_001218

UniProt: P55210

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity