MIB1 anticorps (AA 560-860)
Aperçu rapide pour MIB1 anticorps (AA 560-860) (ABIN6143827)
Antigène
Voir toutes MIB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 560-860
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Séquence
- DSEGDTPLHD AISKKRDDIL AVLLEAGADV TITNNNGFNA LHHAALRGNP SAMRVLLSKL PRPWIVDEKK DDGYTALHLA ALNNHVEVAE LLVHQGNANL DIQNVNQQTA LHLAVERQHT QIVRLLVRAG AKLDIQDKDG DTPLHEALRH HTLSQLRQLQ DMQDVGKVDA AWEPSKNTLI MGLGTQGAEK KSAASIACFL AANGADLSIR NKKGQSPLDL CPDPNLCKAL AKCHKEKVSG QVGSRSPSMI SNDSETLEEC MVCSDMKRDT LFGPCGHIAT CSLCSPRVKK CLICKEQVQS R
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 560-860 of human MIB1/DIP1 (NP_065825.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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Commentaires
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
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Autre désignation
- MIB1
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Sujet
- This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).,MIB1,DIP-1,DIP1,LVNC7,MIB,ZZANK2,ZZZ6,Signal Transduction,Cell Biology & Developmental Biology,Notch Signaling Pathway,Stem Cells,MIB1
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Poids moléculaire
- 110 kDa
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ID gène
- 57534
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UniProt
- Q86YT6
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Pathways
- SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
Antigène
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