MUS81 anticorps (AA 1-350)

N° du produit ABIN6144202

Détail du produit anti-MUS81 anticorps

Antigène: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Épitope: AA 1-350

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUS81 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Séquence: MAAPVRLGRK RPLPACPNPL FVRWLTEWRD EATRSRRRTR FVFQKALRSL RRYPLPLRSG KEAKILQHFG DGLCRMLDER LQRHRTSGGD HAPDSPSGEN SPAPQGRLAE VQDSSMPVPA QPKAGGSGSY WPARHSGARV ILLVLYREHL NPNGHHFLTK EELLQRCAQK SPRVAPGSAR PWPALRSLLH RNLVLRTHQP ARYSLTPEGL ELAQKLAESE GLSLLNVGIG PKEPPGEETA VPGAASAELA SEAGVQQQPL ELRPGEYRVL LCVDIGETRG GGHRPELLRE LQRLHVTHTV RKLHVGDFVW VAQETNPRDP ANPGELVLDH IVERKRLDDL CSSIIDGRFR

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human MUS81 (NP_079404.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MUS81

Antigène: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Autre désignation: MUS81 (MUS81 Produits)

Synonymes: anticorps CG3026, anticorps Dmel\\CG3026, anticorps EG:BACR7A4.16, anticorps MUS81, anticorps GB15332, anticorps ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81, anticorps ATMUS81, anticorps F6I18.220, anticorps F6I18_220, anticorps MMS AND UV SENSITIVE 81, anticorps SLX3, anticorps slx3, anticorps 1200008A18Rik, anticorps AI182501, anticorps AW045863, anticorps wu:fc26g01, anticorps zgc:66489, anticorps zgc:91801, anticorps CG3026 gene product from transcript CG3026-RA, anticorps MUS81 structure-specific endonuclease subunit, anticorps crossover junction endonuclease MUS81, anticorps Restriction endonuclease, type II-like superfamily protein, anticorps Mus81p, anticorps Holliday junction resolvase subunit Mus81, anticorps MUS81 protein, anticorps hypothetical protein, anticorps mus81, anticorps MUS81, anticorps LOC725951, anticorps Mus81, anticorps CAALFM_C600540WA

Sujet: This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.,MUS81,SLX3,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,MUS81

Poids moléculaire: 61 kDa

ID gène: 80198

UniProt: Q96NY9

Pathways: Réparation de l'ADN