MUS81 anticorps

N° du produit ABIN7262745

L’anticorps anti-MUS81 Polyclonal Lapin est utilisé pour la détection de MUS81 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC.

Aperçu rapide pour MUS81 anticorps (ABIN7262745)

Antigène: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUS81 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-MUS81 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human MUS81 (NP_079404.3).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MUS81

Antigène: MUS81 (MUS81 Endonuclease Homolog (MUS81))

Autre désignation: MUS81

Sujet: This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.

ID gène: 80198

UniProt: Q96NY9

Pathways: Réparation de l'ADN