MYLK anticorps (AA 1765-1914)

N° du produit ABIN6144264

Cet anticorps Lapin Polyclonal détecte spécifiquement MYLK dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour MYLK anticorps (AA 1765-1914) (ABIN6144264)

Antigène: MYLK (Myosin Light Chain Kinase (MYLK))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYLK est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-MYLK anticorps

Épitope: AA 1765-1914

Séquence: SGLSGRKSST GSPTSPLNAE KLESEEDVSQ AFLEAVAEEK PHVKPYFSKT IRDLEVVEGS AARFDCKIEG YPDPEVVWFK DDQSIRESRH FQIDYDEDGN CSLIISDVCG DDDAKYTCKA VNSLGEATCT AELIVETMEE GEGEGEEEEE

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1765-1914 of human MYLK (NP_444253.3).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MYLK

Antigène: MYLK (Myosin Light Chain Kinase (MYLK))

Autre désignation: MYLK

Sujet: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.,MYLK,AAT7,KRP,MLCK,MLCK1,MLCK108,MLCK210,MSTP083,MYLK1,s mMLCK,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Actins,MYLK

Poids moléculaire: 16 kDa/80 kDa/110 kDa/197-210 kDa

ID gène: 4638

UniProt: Q15746