PFKFB2 anticorps (AA 446-505)

N° du produit ABIN6145483

Cet anticorps anti-PFKFB2 est un anticorps Lapin Polyclonal détectant PFKFB2 dans WB et IF. Adapté pour Humain.

Aperçu rapide pour PFKFB2 anticorps (AA 446-505) (ABIN6145483)

Antigène: PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFKFB2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-PFKFB2 anticorps

Épitope: AA 446-505

Séquence: RDKPTNNFPK NQTPVRMRRN SFTPLSSSNT IRRPRNYSVG SRPLKPLSPL RAQDMQEGAD

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 446-505 of human PFKFB2 (NP_006203.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PFKFB2

Antigène: PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

Autre désignation: PFKFB2

Sujet: The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.,PFKFB2,PFK-2/FBPase-2,Signal Transduction,PI3K-Akt Signaling Pathway,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,PFKFB2

Poids moléculaire: 54 kDa/58 kDa

ID gène: 5208

UniProt: O60825

Pathways: Signalisation PI3K-Akt, Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process