PIAS3 anticorps (AA 452-628)
Aperçu rapide pour PIAS3 anticorps (AA 452-628) (ABIN6145599)
Antigène
Voir toutes PIAS3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 452-628
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Séquence
- IESSSDEEDL PPTKKHCSVT SAAIPALPGS KGVLTSGHQP SSVLRSPAMG TLGGDFLSSL PLHEYPPAFP LGADIQGLDL FSFLQTESQH YGPSVITSLD EQDALGHFFQ YRGTPSHFLG PLAPTLGSSH CSATPAPPPG RVSSIVAPGG ALREGHGGPL PSGPSLTGCR SDIISLD
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 452-628 of human PIAS3 (NP_006090.2).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))
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Autre désignation
- PIAS3
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Sujet
- This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.,PIAS3,ZMIZ5,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,PIAS3
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Poids moléculaire
- 68 kDa
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ID gène
- 10401
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UniProt
- Q9Y6X2
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Pathways
- Signalistation JAK/STAT
Antigène
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