PKLR anticorps (AA 446-556)
Aperçu rapide pour PKLR anticorps (AA 446-556) (ABIN6145710)
Antigène
Voir toutes PKLR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 446-556
-
Séquence
- PLSRDPTEVT AIGAVEAAFK CCAAAIIVLT TTGRSAQLLS RYRPRAAVIA VTRSAQAARQ VHLCRGVFPL LYREPPEAIW ADDVDRRVQF GIESGKLRGF LRVGDLVIVV T
-
Réactivité croisée
- Humain, Souris, Rat
-
Attributs du produit
- Polyclonal Antibodies
-
Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 446-556 of human PKLR (NP_000289.1).
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB,1:500 - 1:2000
-
Commentaires
-
HIGH QUALITY
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PKLR (Pyruvate Kinase, Liver and RBC (PKLR))
-
Autre désignation
- PKLR
-
Sujet
- The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.,PKLR,PK1,PKL,PKR,PKRL,RPK,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,PKLR
-
Poids moléculaire
- 58 kDa/61 kDa
-
ID gène
- 5313
-
UniProt
- P30613
-
Pathways
- Ribonucleoside Biosynthetic Process
Antigène
-