PLAT anticorps (AA 23-320)

N° du produit ABIN6145743

Cet anticorps Lapin Polyclonal détecte spécifiquement PLAT dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour PLAT anticorps (AA 23-320) (ABIN6145743)

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PLAT anticorps

Épitope: AA 23-320

Séquence: SQEIHARFRR GARSYQVICR DEKTQMIYQQ HQSWLRPVLR SNRVEYCWCN SGRAQCHSVP VKSCSEPRCF NGGTCQQALY FSDFVCQCPE GFAGKCCEID TRATCYEDQG ISYRGTWSTA ESGAECTNWN SSALAQKPYS GRRPDAIRLG LGNHNYCRNP DRDSKPWCYV FKAGKYSSEF CSTPACSEGN SDCYFGNGSA YRGTHSLTES GASCLPWNSM ILIGKVYTAQ NPSAQALGLG KHNYCRNPDG DAKPWCHVLK NRRLTWEYCD VPSCSTCGLR QYSQPQFRIK GGLFADIA

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 23-320 of human tPA/tPA/PLAT (NP_000921.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PLAT

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Autre désignation: PLAT

Sujet: This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,PLAT,T-PA,TPA,Cancer,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,Cardiovascular,Blood,Serum Proteins,Hypoxia,PLAT

Poids moléculaire: 32 kDa/44 kDa/57 kDa/62 kDa

ID gène: 5327

UniProt: P00750

Pathways: Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome