ADRP anticorps (AA 168-437)

N° du produit ABIN6145773

L’anticorps Lapin Polyclonal anti-ADRP a été validé pour WB, IHC et IF. Il convient pour détecter ADRP dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour ADRP anticorps (AA 168-437) (ABIN6145773)

Antigène: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ADRP anticorps

Épitope: AA 168-437

Séquence: MMQLVSSGVE NALTKSELLV EQYLPLTEEE LEKEAKKVEG FDLVQKPSYY VRLGSLSTKL HSRAYQQALS RVKEAKQKSQ QTISQLHSTV HLIEFARKNV YSANQKIQDA QDKLYLSWVE WKRSIGYDDT DESHCAEHIE SRTLAIARNL TQQLQTTCHT LLSNIQGVPQ NIQDQAKHMG VMAGDIYSVF RNAASFKEVS DSLLTSSKGQ LQKMKESLDD VMDYLVNNTP LNWLVGPFYP QLTESQNAQD QGAEMDKSSQ ETQRSEHKTH

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 168-437 of human Perilipin-2 (NP_001113.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Commentaires:

HIGH QUALITY

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-ADRP (ABIN6145773)

Ni, He, Dai, Yao, Guo, Wei: "Oroxylin A suppresses the development and growth of colorectal cancer through reprogram of HIF1α-modulated fatty acid metabolism." dans: Cell death & disease, Vol. 8, Issue 6, pp. e2865, (2018) (PubMed).

Cao, Ruan, Wang, Song, Bao, Xu, Xiao, Wang, Cheng, Tong, Meng, Liu, Yang, Chen, Zhang: "Overexpression of PLIN2 is a prognostic marker and attenuates tumor progression in clear cell renal cell carcinoma." dans: International journal of oncology, Vol. 53, Issue 1, pp. 137-147, (2018) (PubMed).

Détails sur ADRP

Antigène: ADRP (PLIN2) (Perilipin 2 (PLIN2))

Autre désignation: PLIN2

Sujet: The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.,PLIN2,ADFP,ADRP,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Hypoxia,Hypoxia-Regulated,Heart,Lipids,Adipose Related,Cardiovascular diseases,Heart disease,PLIN2

Poids moléculaire: 48 kDa

ID gène: 123

UniProt: Q99541

Pathways: Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism