RSPO1 anticorps (AA 21-263)
Aperçu rapide pour RSPO1 anticorps (AA 21-263) (ABIN6147279)
Antigène
Voir toutes RSPO1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-263
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Séquence
- SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL HKGRCYPACP EGSSAANGTM ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL HAPVGDHAAC SDTKETRRCT VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR RRKGQQQQQQ QGTVGPLTSA GPA
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 21-263 of human RSPO1 (NP_001033722.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- RSPO1 (R-Spondin 1 (RSPO1))
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Autre désignation
- RSPO1
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Sujet
- This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.,RSPO1,CRISTIN3,RSPO,Cell Biology & Developmental Biology,Stem Cells,RSPO1
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Poids moléculaire
- 21 kDa/25 kDa/28 kDa
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ID gène
- 284654
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UniProt
- Q2MKA7
Antigène
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